VANDYCK, Koen,LAST, Stefaan Julien,RABOISSON, Pierre Jean-Marie Bernard
申请号：
ES14707372
公开号：
ES2628953T3
申请日:
2014.02.27
申请国别(地区):
ES
年份:
2017
代理人:
摘要：
A compound of Formula (I) ** Formula ** or a stereoisomer or tautomeric form thereof, in which: R 1 represents hydrogen； R2 represents C1-C8 alkyl substituted with one or more R5, R3 represents hydrogen or methyl； R4 represents methyl； Each R5 is independently selected from the group consisting of: -C≡CH, -CN, -OH, oxo, C1-C4 alkyloxy, -C (>； = O) O-R6, -C (>； = O) N (R6 ) 2, -N (R6) 2, -NR9C (>； = O) -R6, -NR9C (>； = O) O-R6 and SO2R9； Each R6 independently represents hydrogen or C1-C3 alkyl； R9 represents hydrogen or C1-C3 alkyl； or a pharmaceutically acceptable salt or solvate thereof.Un compuesto de la Fórmula (I)**Fórmula** o un estereoisómero o forma tautómera del mismo, en el que: R1 representa hidrógeno； R2 representa alquilo C1- C8 sustituido con uno o más R5, R3 representa hidrógeno o metilo； R4 representa metilo； Cada R5 se selecciona independientemente del grupo que consiste en: -C≡CH, -CN, -OH, oxo, alquiloxi C1- C4, -C(>；=O)O-R6, -C(>；=O)N(R6)2, -N(R6)2, -NR9C(>；=O)-R6, -NR9C(>；=O)O-R6 y SO2R9； Cada R6 representa independientemente hidrógeno o alquilo C1-C3； R9 representa hidrógeno o alquilo C1-C3； o una sal o un solvato farmacéuticamente aceptable del mismo.
