A walking assistance device providing an assistance force to a user is provided. The device compensates for an influence of an inertial force of the device itself. An actuator drives leg joints such that a total sum of supporting forces acting on the leg links from a floor side is a target total lifting force. The total sum of supporting forces acting on leg links from a floor side in reaction to a vertical inertial force generated in the device due to a motion of the device and the gravity acting on the device is estimated as a force which compensates for the self weight of the device. The total sum of a target value of a lifting force to be applied to the user and the estimated value of the force which compensates for the self weight of the device is defined as a target total lifting force.