An antiallergic agent for topical administration containing an adenine compound of general formula (1):[wherein ring A represents a 6 to 10 membered, mono or bicyclic, aromatic hydrocarbon or a 5 to 10 membered, mono or bicyclic, aromatic heterocycle containing one to three heteroatoms selected among 0 to 2 nitrogen atoms, 0 or 1 oxygen atom, and 0 or 1 sulfur atom； n is an integer of 0 to 2； m is an integer of 0 to 2； R represents halogeno, (un)substituted alkyl, etc.； X1 represents oxygen, sulfur, NR1 (R1 represents hydrogen or alkyl), or a single bond； Y1 represents a single bond, alkylene, etc.； Y2 represents a single bond, alkylene, etc.； Z represents alkylene； and at least one of Q1 and Q2 represents —COOR10 (wherein R10 represents (un)substituted alkyl, etc.), etc.] or a pharmaceutically acceptable salt of the compound.
