Disclosed herein are methods for use of R-chloroquine or clemizole or combinations of R-chloroquine and clemizole for the treatment of a subject in need thereof. Uses include methods of treating inflammatory conditions, treating liver cancer or reducing the risk of developing liver cancer in a subject. Uses also include methods of treating non-alcoholic steatohepatitis in a subject.本文揭示使用R-氯喹(R-chloroquine)或克立咪唑(clemizole)或R-氯喹及克立咪唑之組合以治療需要其之個體之方法。用途包含治療個體中發炎病況、治療肝癌或降低罹患肝癌之風險之方法。用途亦包含治療個體中非酒精性脂肪性肝炎之方法。