Disclosed herein are substituted azole dione compounds of structure (II), wherein X is NR3, R3 is H, alkyl, or acyl; A is N or CH; B is CR8 or N and the other substituents are as defined within the specification, processes for its preparation, compositions comprising said compounds and uses thereof. Said compounds have useful anti-cancer activity and/or activity against proliferating cells and as such is useful in the treatment of cell proliferative disorders, i.e. lymphoma, myeloma, leukemia.