Compounds derived from N - [(2 - oxo - 1,2 dihydro - 3-pyridinyl) methyl] - 1H indole - 3 - carboxamide,Inhibitors of Ezh2； Pharmaceutical composition containing； useful in Cancer Treatment selected from the group consisting of Brain glioblastomas (gliomas), leukemias and lymphomas.And disorders mediated by inhibition of Ezh2.
BURGESS, JOELLE LORRAINE,JOHNSON, NEIL,LaFRANCE, LOUIS,NEWLANDER, KENNETH,ROMERIL, STUART,ROUSE, MEAGAN B.,TIAN, XINRONG: BRACKLEY, JAMES,KNIGHT, STEVEN D.,MILLER, WILLIAM H.,GRANT, S
申请号：
CL2012003110
公开号：
CL2012003110A1
申请日:
2012.11.06
申请国别(地区):
CL
年份:
2013
代理人:
摘要：
Compounds derived from N - [(2 - oxo - 1,2 dihydro - 3-pyridinyl) methyl] - 1H indole - 3 - carboxamide inhibitors of Ezh2； method to treat cancer selected from the group consisting of Brain gliomas),Glioblastomas, leukemias and lymphomas, among others； and its use for the treatment of a disorder mediated by inhibition of Ezh2.<；p>；SE DESCRIBE INDOLES DE FORMULA (I) DONDE LOS DIVERSOS GRUPOS SE DEFINEN EN ESTE DOCUMENTO, COMPOSICIONES FARMACÉ；UTICAS QUE LOS CONTIENEN, QUE SON Ú；TILES PATA EL TRATAMIENTO DEL CÁ；NCER.<；/p>；
