The invention provides a sober-up device which is characterized by comprising a sober-up vessel a base, an oxygen production device and a circuit control device. The base is movably connected with the sober-up vessel. The oxygen production device is communicated with the sober-up vessel through an oxygen output tube. The sober-up device has the advantages that the device is capable of dispelling the effects of alcohol automatically, good in sober-up effect, multifunctional and convenient to use the sober-up time can be controlled oxygen concentration can be adjusted according to liquor of different years so as to achieve a better effect, or appropriate time and oxygen concentration can be automatically set by selecting corresponding liquor selection keys according to different kinds of liquor so as to dispel the effects of alcohol.