DIFLUOROLACTAM COMPOUNDS AS EP4 RECEPTOR-SELECTIVE AGONISTS FOR USE IN THE TREATMENT OF EP4-MEDIATED DISEASE AND CONDITIONS

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专利权人:

Cayman Chemical Company; Incorporated

发明人:

申请号：

EP16192438.6

公开号：

EP3176162A1

申请日:

2013.07.19

申请国别(地区):

EP

年份:

2017

代理人:

摘要：

Disclosed herein are compounds of formula (I)and therapeutic methods of treatment with compounds of formula (I), wherein L1, L2, L4, R1, R4, R5, R6, and s are as defined in the specification. Compounds of formula (I) are EP4 agonists useful in the treatment of glaucoma, neuropathic pain, and related disorders.

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