Stephen Douglas Barrett,Fred Lawrence Ciske,Joseph Michael Colombo,Gregory William Endres,Bradlee David Germain,Andriy Kornilov,James Bernard Kramer,Adam Uzieblo,Kirk M. Maxey
申请号:
US14872967
公开号:
US09487478B2
申请日:
2015.10.01
申请国别(地区):
US
年份:
2016
代理人:
摘要:
Disclosed herein are compounds of formula (I)and therapeutic methods of treatment with compounds of formula (I), wherein L1, L2, L4, R1, R4, R5, R6, and s are as defined in the specification. Compounds of formula (I) are EP4 agonists useful in the treatment of glaucoma, neuropathic pain, and related disorders.