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DIFLUOROLACTAM COMPOUNDS AS EP4 RECEPTOR-SELECTIVE AGONISTS FOR USE IN THE TREATMENT OF EP4-MEDIATED DISEASES AND CONDITIONS
专利权人:
Cayman Chemical Company; Inc.
发明人:
Stephen Douglas Barrett,Fred Lawrence Ciske,Joseph Michael Colombo,Gregory William Endres,Bradlee David Germain,Andriy Kornilov,James Bernard Kramer,Adam Uzieblo,Kirk M. Maxey
申请号:
US16732537
公开号:
US20200207709A1
申请日:
2020.01.02
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Disclosed herein are compounds of formula (I)and therapeutic methods of treatment with compounds of formula (I), wherein L1, L2, L4, R1, R4, R5, R6, and s are as defined in the specification. Compounds of formula (I) are EP4 agonists useful in the treatment of glaucoma, neuropathic pain, and related disorders.
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