PAUL CARTER,CHRISTOPH SPIESS,YIYUAN YIN,JIANHUI ZHOU,WENDY SANDOVAL,JACOB CORN,MICHAEL DILLON
申请号:
US15789670
公开号:
US20180177873A1
申请日:
2017.10.20
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Provided are, inter alia, multispecific antigen binding proteins, or antigen-binding fragments thereof, comprising one or more mutations in the VH/VL domains and/or CH1/CL domains, pharmaceutical compositions comprising same, isolated nucleic acids, vectors, and host cells encoding/expressing same, method of making the multispecific antigen binding proteins, computer readable media for evaluating multispecific antigen binding proteins, and libraries.