CARTER, PAUL,SPIESS, CHRISTOPH,YIN, YIYUAN,ZHOU, JIANHUI,SANDOVAL, WENDY,CORN, JACOB,DILLON, MICHAEL
申请号:
CA2980189
公开号:
CA2980189A1
申请日:
2016.04.22
申请国别(地区):
CA
年份:
2016
代理人:
摘要:
Provided are, inter alia, multispecific antigen binding proteins, or antigen-binding fragments thereof, comprising one or more mutations in the VH/VL domains and/or CH1/CL domains, pharmaceutical compositions comprising same, isolated nucleic acids, vectors, and host cells encoding/expressing same, method of making the multispecific antigen binding proteins, computer readable media for evaluating multispecific antigen binding proteins, and libraries.