Carter, Paul,Spiess, Christoph,Yin, Yiyuan,Zhou, Jianhui,Sandoval, Wendy,Corn, Jacob,Dillon, Michael
申请号:
AU2016252773
公开号:
AU2016252773A1
申请日:
2016.04.22
申请国别(地区):
AU
年份:
2017
代理人:
摘要:
Provided are, inter alia, multispecific antigen binding proteins, or antigen-binding fragments thereof, comprising one or more mutations in the VH/VL domains and/or CH1/CL domains, pharmaceutical compositions comprising same, isolated nucleic acids, vectors, and host cells encoding/expressing same, method of making the multispecific antigen binding proteins, computer readable media for evaluating multispecific antigen binding proteins, and libraries.