PROBLEM TO BE SOLVED: To provide a targeting molecule which targets target cells selected from the group consisting of stellate cells, myofibroblasts, cancer associated fibroblasts, tumor cells, and STRA6 expression cells.SOLUTION: The invention relates to a targeting molecule selected from the group consisting of (1) a peptide comprising an amino acid sequence in a cell-binding region of RBP, (2) a variant peptide of the peptide having targeting ability equivalent to the peptide of (1), and (3) a peptidomimetic material having targeting ability equivalent to the peptide of (1) or (2) a targeting agent, carrier, conjugate, and pharmaceutical composition containing the targeting molecule a method for treating, detecting, diagnosing, or monitoring diseases associated with the cells and a method for labeling, detecting, or imaging the cells.COPYRIGHT: (C)2016,JPO&INPIT【課題】星細胞、筋線維芽細胞、がん随伴線維芽細胞、腫瘍細胞およびSTRA6発現細胞からなる群から選択される標的細胞を標的化する標的化分子等を提供する。【解決手段】(1)RBPの細胞結合領域のアミノ酸配列を含むペプチド、(2)(1)のペプチドと同等の標的化能を有する該ペプチドの変異体ペプチド、(3)(1)または(2)のペプチドと同等の標的化能を有するペプチド模倣物、からなる群から選択される標的化分子、該標的化分子を含む標的化剤、担体、複合体および医薬組成物、前記細胞に関連する疾患を処置、検査、診断またはモニタリングする方法、および、前記細胞を標識、検出またはイメージングする方法。【選択図】なし
