Katherine S. Bowdish,John McWhirter,Anke Kretz-Rommel,Toshiaki Maruyama
申请号：
US12715303
公开号：
US08114403B2
申请日:
2010.03.01
申请国别(地区):
US
年份:
2012
代理人:
摘要：
Cancer treatments use a therapy that: 1) interferes with the interaction between CD200 and its receptor to block immune suppression thereby promoting eradication of the cancer cells and 2) directly kills the cancer cells either by complement-mediated or antibody-dependent cellular cytotoxicity or by targeting cells using a fusion molecule that includes a CD200-targeting portion. The therapy includes the administration of novel antibodies, functional fragments thereof or fusion molecules containing portions thereof.
