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COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT
专利权人:
Ardelyx; Inc.
发明人:
Jason G. Lewis,Jeffrey W. Jacobs,Nicholas Reich,Michael R. Leadbetter,Noah Bell,Han-Ting Chang,Tao Chen,Marc Navre,Dominique Charmot,Christopher Carreras,Eric Labonte
申请号:
US14329821
公开号:
US20150157637A1
申请日:
2014.07.11
申请国别(地区):
US
年份:
2015
代理人:
摘要:
Compounds having activity as phosphate transport inhibitors, more specifically, inhibitors of intestinal apical membrane Na/phosphate co-transport, are disclosed. The compounds have the following structure (I):including stereoisomers, pharmaceutically acceptable salts and prodrugs thereof, wherein X, Y and A are as defined herein. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.
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