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COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT
专利权人:
Ardelyx; Inc.
发明人:
Jason G. Lewis,Jeffrey W. Jacobs,Nicholas Reich,Michael R. Leadbetter,Noah Bell,Han-Ting Chang,Tao Chen,Marc Navre,Dominique Charmot,Christopher Carreras,Eric Labonte
申请号:
US13734701
公开号:
US20130336919A1
申请日:
2013.01.04
申请国别(地区):
US
年份:
2013
代理人:
摘要:
Compounds having activity as phosphate transport inhibitors, more specifically, inhibitors of intestinal apical membrane Na/phosphate co-transport, are disclosed. The compounds have the following structure (I):including stereoisomers, pharmaceutically acceptable salts and prodrugs thereof, wherein X, Y, R1 and R2 are as defined herein. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.
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