Jason G. Lewis,Jeffrey W. Jacobs,Nicholas Reich,Michael R. Leadbetter,Noah Bell,Han-Ting Chang,Tao Chen,Marc Navre,Dominique Charmot,Christopher Carreras,Eric Labonte
申请号：
US13734547
公开号：
US08916569B2
申请日:
2013.01.04
申请国别(地区):
US
年份:
2014
代理人:
摘要：
Compounds having activity as phosphate transport inhibitors, more specifically, inhibitors of intestinal apical membrane Na/phosphate co-transport, are disclosed. The compounds have the following structure (I):including stereoisomers, pharmaceutically acceptable salts and prodrugs thereof, wherein X, Y, A, R1 and R2 are as defined herein. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.
