HILL, OLIVER,GIEFFERS, CHRISTIAN,THIEMANN, MEINOLF,BUCHANAN, FRITZ, G.,PHILLIPS, DARREN, C.,LAPPE, SUSAN, E.
申请号:
RSP20180450
公开号:
RS57153B1
申请日:
2015.04.23
申请国别(地区):
RS
年份:
2018
代理人:
摘要:
Provided herein are specific TRAIL receptor agonist proteins, nucleic acids encoding the same, and methods of treating a subject having a TRAIL-associated disease or disorder. The TRAIL receptor agonist proteins provided herein comprise three soluble TRAIL domains and an Fc fragment. The TRAIL receptor agonist proteins are substantially non-aggregating and suitable for therapeutic, diagnostic and/or research applications.