HILL, Oliver,GIEFFERS, Christian,THIEMANN, Meinolf,BUCHANAN, Fritz,PHILLIPS, Darren,LAPPE, Susan
申请号:
LT15721089
公开号:
LT3134430T
申请日:
2015.04.23
申请国别(地区):
LT
年份:
2018
代理人:
摘要:
Provided herein are specific TRAIL receptor agonist proteins, nucleic acids encoding the same, and methods of treating a subject having a TRAIL-associated disease or disorder. The TRAIL receptor agonist proteins provided herein comprise three soluble TRAIL domains and an Fc fragment. The TRAIL receptor agonist proteins are substantially non-aggregating and suitable for therapeutic, diagnostic and/or research applications.