HILL, OLIVER,GIEFFERS, CHRISTIAN,THIEMANN, MEINOLF,BUCHANAN, FRITZ G.,PHILLIPS, DARREN C.,LAPPE, SUSAN E.
申请号：
CA2946402
公开号：
CA2946402A1
申请日:
2015.04.23
申请国别(地区):
CA
年份:
2015
代理人:
摘要：
Provided herein are specific TRAIL receptor agonist proteins, nucleic acids encoding the same, and methods of treating a subject having a TRAIL-associated disease or disorder. The TRAIL receptor agonist proteins provided herein comprise three soluble TRAIL domains and an Fc fragment. The TRAIL receptor agonist proteins are substantially non-aggregating and suitable for therapeutic, diagnostic and/or research applications.
