HILL OLIVER,GIEFFERS CHRISTIAN,THIEMANN MEINOLF,BUCHANAN FRITZ G,PHILLIPS DARREN C,LAPPE SUSAN E
申请号:
IN201617038061
公开号:
IN201617038061A
申请日:
2016.11.08
申请国别(地区):
IN
年份:
2017
代理人:
摘要:
Provided herein are specific TRAIL receptor agonist proteins nucleic acids encoding the same and methods of treating a subject having a TRAIL associated disease or disorder. The TRAIL receptor agonist proteins provided herein comprise three soluble TRAIL domains and an Fc fragment. The TRAIL receptor agonist proteins are substantially non aggregating and suitable for therapeutic diagnostic and/or research applications.