KOHNKE, FRANZ HEINRICH,IZZOTTI, ALBERTO,ROSANO, CAMILLO,CAFEO, GRAZIA
申请号：
CA3042365
公开号：
CA3042365A1
申请日:
2017.09.26
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
Calixpyrrole-based antitumor compounds are described, which can be derivatized to obtain their passive transport on tumor masses through the Enhanced Permeation and Retention, EPR, effect of the neoplastic vasculature. The conjugation of the above mentioned compounds with peptides/antibodies is further described, for their possible active transport on tumor cells.
