UNIVERSITA' DEGLI STUDI DI MESSINA;UNIVERSITA DEGLI STUDI DI MESSINA
发明人:
Kohnke, Franz Heinrich,Izzotti, Alberto,Rosano, Camillo,Cafeo, Grazia,KOHNKE FRANZ HEINRICH,IZZOTTI ALBERTO,ROSANO CAMILLO,CAFEO GRAZIA
申请号：
IT201600097521
公开号：
IT201600097521A1
申请日:
2016.09.29
申请国别(地区):
IT
年份:
2016
代理人:
摘要：
Calixpyrrole-based antitumor compounds are described, which can be derivatized to obtain their passive transport on tumor masses through the Enhanced Permeation and Retention, EPR, effect of the neoplastic vasculature. The conjugation of the above mentioned compounds with peptides/antibodies is further described, for their possible active transport on tumor cells.
