Franz Heinrich Kohnke,Alber Izzotti,Camillo Rosano,Grazia Cafeo
申请号：
US16337532
公开号：
US20190224167A1
申请日:
2017.09.26
申请国别(地区):
US
年份:
2019
代理人:
摘要：
Calixpyrrole-based antitumor compounds are described, which can be derivatized to obtain their passive transport on tumor masses through the Enhanced Permeation and Retention, EPR, effect of the neoplastic vasculature. The conjugation of the above mentioned compounds with peptides/antibodies is further described, for their possible active transport on tumor cells.
