Benoit Christophe Stephan CALLENDRET,Kerstin LUHN-WEGMANN
申请号:
US16500567
公开号:
US20200101153A1
申请日:
2018.04.06
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Compositions and methods are described for generating an improved effective immune response against an immunogen in humans. The enhanced immune response, is obtained by using an MVA vector as a prime, an adenovirus vector as a first boost, and an adenovirus vector as a second boost. The compositions and methods can be used to provide a protective immunity against a disease, such as an infection of one or more subtypes of Ebola and Marburg filoviruses, in humans.