THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY DEPARTMENT OF HEALTH AND HUMAN SERVICES;JANSSEN VACCINES AND PREVENTION B.V.;BAVARIAN NORDIC A/S
发明人:
申请号：
IL25081817
公开号：
IL250818D0
申请日:
2017.02.27
申请国别(地区):
IL
年份:
2017
代理人:
摘要：
Compositions and methods are described for generating an improved effective immune response against an immunogen in humans. The enhanced immune response, is obtained by using an MVA vector as a prime and an adenovirus vector as a boost and is characterized by a high level of antibody response specific to the immunogen, and an enhanced cellular immune response. The compositions and methods can be used to provide a protective immunity against a disease, such as an infection of one or more subtypes of Ebola and Marburg filoviruses, in humans.
