Provided is a crystal of a novel pyrido[3, 4-d]pyrimidine derivative having excellent CDK 4/6 inhibitory activity. A crystal of a compound represented by formula (I). In the formula, Rrepresents a hydrogen atom or a Calkyl group; Rrepresents a hydrogen atom or an oxo group; L represents a single bond or a Calkylene group; and X represents CH or N.