Alison Jo-Anne WOOLFORD,Steven HOWARD,Ildiko Maria BUCK,Gianni CHESSARI,Christopher Norbert JOHNSON,Emiliano TAMANINI,James Edward Harvey DAY,Elisabetta CHIARPARIN,Thomas Daniel HEIGHTMAN,Martyn FREDE
申请号:
US16409364
公开号:
US20190375748A1
申请日:
2019.05.10
申请国别(地区):
US
年份:
2019
代理人:
摘要:
The invention relates to bicyclic heterocycle compounds of formula (I):or tautomeric or stereochemically isomeric forms, N-oxides, pharmaceutically acceptable salts or the solvates thereof; wherein R1, R2a, R2b, R3a, R3b, R5, R6, R7, R8, R9, p and E are as defined herein; to pharmaceutical compositions comprising said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer.