Martyn Frede;Steven Howard;Ildiko Maria Buck;Emiliano Tamanini;James Edward Harvey Day;Elisabetta Chiarparin;Christopher Norbert Johnson;Thomas Daniel Heightman;Alison Jo-Anne Woolford;Gianni Chessari
发明人:
Alison Jo-Anne Woolford,Steven Howard,Ildiko Maria Buck,Gianni Chessari,Christopher Norbert Johnson,Emiliano Tamanini,James Edward Harvey Day,Elisabetta Chiarparin,Thomas Daniel Heightman,Martyn Frede
申请号：
US14112597
公开号：
US09018214B2
申请日:
2012.04.20
申请国别(地区):
US
年份:
2015
代理人:
摘要：
The invention relates to bicyclic heterocycle compounds of formula (I): or tautomeric or stereochemically isomeric forms, N-oxides, pharmaceutically acceptable salts or the solvates thereof； wherein R1, R2a, R2b, R3a, R3b, R5, R6, R7, R8, R9, p and E are as defined herein； to pharmaceutical compositions comprising said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer.
