Alison Jo-Anne Woolford,Steven Howard,Ildiko Maria Buck,Gianni Chessari,Christopher Norbert Johnson,Emiliano Tamanini,James Edward Harvey Day,Elisabetta Chiarparin,Thomas Daniel Heightman,Martyn Frede
申请号:
US14663534
公开号:
US09676768B2
申请日:
2015.03.20
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The invention relates to bicyclic heterocycle compounds of formula (I):or tautomeric or stereochemically isomeric forms, N-oxides, pharmaceutically acceptable salts or the solvates thereof; wherein R1, R2a, R2b, R3a, R3b, R5, R6, R7, R8, R9, p and E are as defined herein; to pharmaceutical compositions comprising said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer.