Janet Mabel Scott Skakle;Jordan Christopher Conway;Iain Ronald Gibson;Basil Annaz
发明人:
Iain Ronald Gibson,Janet Mabel Scott Skakle,Jordan Christopher Conway,Basil Annaz
申请号：
US13806243
公开号：
US09492591B2
申请日:
2011.06.22
申请国别(地区):
US
年份:
2016
代理人:
摘要：
The bone graft system comprises a solid inorganic component, which is bone graft material, and a hydrogel. The hydrogel contains >；2 ppm of silicon ions, calculated as parts by weight of Si per million of the aqueous component of the hydrogel. Preferably, the solid inorganic component comprises hydroxyapatite or a silicon-containing hydroxyapatite, and may be a silicon-containing hydroxyapatite having a Ca/P ratio in the range 2.05 to 2.55 and a Ca/(P+Si) molar ratio less than 1.66. Bone healing is promoted by delivery of silicon ion release from the hydrogel and by the solid inorganic component stimulating cell behavior.
