YAMANOI, Shigeo,NAMIKI, Hidenori,OCHIAI, Yuichi,HOSHINO, Madoka,MATSUMOTO, Koji
申请号：
ES15192148
公开号：
ES2640667T3
申请日:
2013.01.17
申请国别(地区):
ES
年份:
2017
代理人:
摘要：
A compound represented by the general formula (I): ** Formula ** in which ring A represents ** Formula ** * represents the binding site with benzene ring, X represents CH or N, R1 represents -C (>； = O) -NH-R5, -NH-C (>； = O) -NH-R5 or -S (>； = O) 2-R5, R2 represents -F or -H R3 represents -CH3 or -C2H5 R4 represents ** Formula ** R5 represents -H, or represents a C1-C6 alkyl group, a C3-C6 cycloalkyl group, or ** Formula ** each of which may be substituted with 1 to 3 -OH, or a pharmaceutically acceptable salt thereof.Un compuesto representado por la fórmula general (I):**Fórmula** en la que el anillo A representa**Fórmula** * representa el sitio de unión con el anillo de benceno, X representa CH o N, R1 representa -C(>；=O)-NH-R5, -NH-C(>；=O)-NH-R5 o -S(>；=O)2-R5, R2 representa -F o -H R3 representa -CH3 o -C2H5 R4 representa**Fórmula** R5 representa -H, o representa un grupo alquilo C1-C6, un grupo cicloalquilo C3-C6, o**Fórmula** cada uno de los cuales puede estar sustituido con 1 a 3 -OH, o una sal farmacéuticamente aceptable del mismo.
