Frank Derosa,Lianne Smith,Michael Heartlein,Braydon Charles Guild
申请号：
US14775818
公开号：
US10130649B2
申请日:
2014.03.14
申请国别(地区):
US
年份:
2018
代理人:
摘要：
Disclosed herein are pharmaceutical compositions that comprise “blends” of lipid nanoparticles and related methods of using such blended compositions to deliver polynucleotides to one or more target cells, tissues or organs. The blended compositions are generally characterized as being able to efficiently deliver polynucleotides to target cells and by their ability to enhance the expression of such polynucleotides and the production of functional proteins by target cells.
