DEROSA, Frank,SMITH, Lianne,HEARTLEIN, Michael,Guild, Braydon Charles
申请号:
DK18160237
公开号:
DK3388834T3
申请日:
2014.03.14
申请国别(地区):
DK
年份:
2020
代理人:
摘要:
Disclosed herein are pharmaceutical compositions that comprise "blends" of lipid nanoparticles and related methods of using such blended compositions to deliver polynucleotides to one or more target cells, tissues or organs. The blended compositions are generally characterized as being able to efficiently deliver polynucleotides to target cells and by their ability to enhance the expression of such polynucleotides and the production of functional proteins by target cells.