MEDICAMENTO PARA TRATAR INFLUENZA CARACTERIZADO PORQUE COMPRENDE UNA COMBINACION DE UN INHIBIDOR DE ENDONUCLEASA DEPENDIENTE DE CASQUETE CON UN FARMACO ANTI-INFLUENZA.
A) Formula (I) A medicine that is useful for treating or preventing influenza, etc., said medicine being characterized by comprising a combination of: (A) a compound represented by formula (I), a pharmaceutically acceptable salt thereof, or a solvate of the same [in formula (I): P represents a hydrogen atom or a prodrug-forming group； A1 represents CR1AR1B, S or O； A2 represents CR2AR2B, S or O； A3 represents CR3AR3B, S or O； A4's independently represent CR4AR4B, S or O； (wherein: the ring-constituting atoms of the ring formed by A1, A2, A3, A4's, the nitrogen atom adjacent to A1 and the carbon atom adjacent to A4's include 1 or 2 hetero atoms； R1A and R1B independently represent a hydrogen atom, halogen, alky, etc.； R2A and R2B independently represent a hydrogen atom, halogen, alky, etc.； R3A and R3B independently represent a hydrogen atom, halogen, alky, etc.； R4A's independently represent a hydrogen atom, halogen, alky, etc.； R4B's independently represent a hydrogen atom, halogen, alky, etc.； and R3A and R3B may form, together with the carbon atom adjacent thereto, a non-aromatic carbon ring or a non-aromatic heterocyclic ring)； n is an integer of 1-2； and R1 is a group represented by formula (2), etc.]； with (B) a compound having an anti-influenza effect, a pharmaceutically acceptable salt thereof, or a solvate of the same, and/or an antibody having an anti-influenza effect.Un medicamento caracterizado porque (A) un compuesto representado por la fórmula (I): (ver Fórmula) su sal farmacéuticamente aceptable, o un solvato del mismo, en donde P es hidrógeno o un grupo para formar un profármaco: A1 es CR1AR1B, S u O； A2 es CR2AR2B, S u O； A3 es CR3AR3B, S u O； A4 es cada uno independientemente CR4AR4B, S u O； el número de heteroátomos entre los átomos que constituyen el anillo que consiste de A1, A2, A3, A4, el átomo de nitrógeno adyacente a A1 y el átomo de carbono adyacente a A4 es 1 o 2； R1A y R1B son cada uno independientemente hidrógeno, halógeno, alquilo, halo
