RANA THERAPEUTICS, INC;THE GENERAL HOSPITAL CORPORATION D/B/A MASSACHUSETTS GENERAL HOSPITAL
发明人:
ARTHUR M. KRIEG,JAMES MCSWIGGEN,JEANNIE T. LEE,ROMESH SUBRAMANIAN
申请号：
BR112014028647
公开号：
BR112014028647A2
申请日:
2013.05.16
申请国别(地区):
BR
年份:
2017
代理人:
摘要：
Aspects of the invention provide single stranded oligonucleotides for activating or enhancing expression of BDNF. Further aspects provide compositions and kits comprising single stranded oligonucleotides for activating or enhancing expression of BDNF. Methods for modulating expression of BDNF using the single stranded oligonucleotides are also provided. Further aspects of the invention provide methods for selecting a candidate oligonucleotide for activating or enhancing expression of BDNF.
