RaNA Therapeutics, Inc.;The General Hospital Corporation d/b/a Massachuset General Hospital
发明人:
Arthur M. Krieg,Romesh Subramanian,James McSwiggen,Jeannie T. Lee
申请号：
US14401234
公开号：
US20150133529A1
申请日:
2013.05.16
申请国别(地区):
US
年份:
2015
代理人:
摘要：
Aspects of the invention provide single stranded oligonucleotides for activating or enhancing expression of BDNF. Further aspects provide compositions and kits comprising single stranded oligonucleotides for activating or enhancing expression of BDNF. Methods for modulating expression of BDNF using the single stranded oligonucleotides are also provided. Further aspects of the invention provide methods for selecting a candidate oligonucleotide for activating or enhancing expression of BDNF.
