THE GENERAL HOSPITAL CORPORATION D/B/A MASSACHUSETTS GENERAL HOSPITAL;RANA THERAPEUTICS INC.
发明人:
KRIEG, ARTHUR, M.,SUBRAMANIAN, ROMESH,MCSWIGGEN, JAMES,LEE, JEANNIE, T.
申请号：
EP13790378
公开号：
EP2849800A4
申请日:
2013.05.16
申请国别(地区):
EP
年份:
2015
代理人:
摘要：
Aspects of the invention provide single stranded oligonucleotides for activating or enhancing expression of BDNF. Further aspects provide compositions and kits comprising single stranded oligonucleotides for activating or enhancing expression of BDNF. Methods for modulating expression of BDNF using the single stranded oligonucleotides are also provided. Further aspects of the invention provide methods for selecting a candidate oligonucleotide for activating or enhancing expression of BDNF.
