John Latham;Jeffrey T. L. Smith;Randall C. Schatzman;Mark J. Litton
发明人:
Jeffrey T. L. Smith,Randall C. Schatzman,Mark J. Litton,John Latham
申请号:
US13046860
公开号:
US09546213B2
申请日:
2011.03.14
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The present invention is directed to therapeutic methods using antibodies and fragments thereof having binding specificity for IL-6 to prevent or treat cachexia, fever, weakness and/or fatigue in a patient in need thereof. In preferred embodiments these patients will comprise those exhibiting (or at risk of developing) an elevated serum C-reactive protein level. In another preferred embodiment, the patient's survivability or quality of life will preferably be improved.