The invention provides novel compounds having the general formula I: wherein R1, the A ring and the B ring are as described herein, pharmaceutical compositions including the compounds, and methods of using the compounds.本發明提供具有通式I之新穎化合物: 其中R1、A環及B環係如本文所述;包括該等化合物之醫藥組合物;及使用該等化合物之方法。