ALI Amjad,ALI Amjad,LO Michael Man-Chu,LO Michael Man-Chu,LIM Yeon-Hee,LIM Yeon-Hee,STAMFORD Andrew,STAMFORD Andrew,KUANG Rongze,KUANG Rongze,TEMPEST Paul,TEMPEST Paul,YU Younong,YU Younong,HUANG Xian
申请号:
SI201330980
公开号:
SI2945632T1
申请日:
2013.12.20
申请国别(地区):
SI
年份:
2018
代理人:
摘要:
Disclosed are compounds of Formula G1 (structurally represented): where &ldquoRG3&rdquo&ldquoRd1&rdquo to &ldquoRd4&rdquo, &ldquon&rdquo, &ldquom&rdquo, &ldquop&rdquo, &ldquoW&rdquo, &ldquoX&rdquo, &ldquoY&rdquo, and &ldquoZ&rdquo are defined herein which compounds are antagonists of A2A receptor. Disclosed herein also are uses of the compounds described herein as antagonists of the A2a receptor in the potential treatment or prevention of neurological disorders and diseases in which A2A receptors are involved. Disclosed herein also are pharmaceutical compositions comprising these compounds and uses of these pharmaceutical compositions.