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Concentrated pyridine and triazine and their application
专利权人:
BAYER INTELLECTUAL PROPERTY GMBH
发明人:
FOLLMANN, MARKUS,STASCH, JOHANNES-PETER,REDLICH, GORDEN,ACKERSTAFF, JENS,GRIEBENOW, NILS,KNORR, ANDREAS,WUNDER, FRANK,LI, VOLKHART MIN-JIAN,KROH, WALTER,BARFACKER, LARS
申请号:
PE2013000009
公开号:
PE20130779A1
申请日:
2011.07.05
申请国别(地区):
PE
年份:
2013
代理人:
摘要:
It refers to pyridine compounds and zinc trichloride in formula (I), wherein a is n, CR3; R3 is h, fluorine, difluoromethane, etc.; L is prior to dimethyl, cyclopropene, carbon trifluoride, etc.; R1 is h; fluorination; R2 is a substitute for 1 to 3 fluorination, etc. Formic butylcarboxylate methyl, {2 - {2 - [2 - [2 - [2 - [1 - [2 - (2 - [2.3-d] pyridine-5-il} acetic,There are others He also mentioned a program and a pharmaceutical composer. These compounds can be used to treat cardiovascular diseases.SE REFIERE A COMPUESTOS PIRIMIDINAS Y TRIAZINAS CONDENSADAS DE FORMULA (I) DONDE A ES N, CR3; R3 ES H, FLUOR, DIFLUOROMETILO, ENTRE OTROS; L ES DE PREFERENCIA DIMETIL, CICLOPROPIL, TRIFLUORCARBONO, ENTRE OTROS; R1 ES H; FLUOR; R2 ES BENCILO SUSTITUIDO CON 1 A 3 SUSTITUYENTES FLUOR, ENTRE OTROS. SON COMPUESTOS PREFERIDOS: {2-[1-(2-FLUOROBENCIL)-1H-PIRAZOLO[3,4-b]PIRIDIN-3-IL]-5-HIDROXI-6-OXO-6,7-DIHIDRO-5H-PIRROLO[2,3-d]PIRIMIDIN-5-IL}ACETATO DE TERC-BUTILO, {2-[1-(2-FLUOROBENCIL)-1H-PIRAZOLO[3,4-b]PIRIDIN-3-IL]-5-HIDROXI-6-OXO-6,7-DIHIDRO-5H-PIRROLO[2,3-d]PIRIMIDIN-5-IL}ACETICO, ENTRE OTROS. SE REFIERE TAMBIEN A UN PROCEDIMIENTO Y UNA COMPOSICION FARMACEUTICA. DICHOS COMPUESTOS SON UTILES EN EL TRATAMIENTO DE TRASTORNOS CARDIOVASCULARES.
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