Refers to pyrimidines and Triazines Condensed compounds of formula (i) where a is n, CR3 R3 is H, Fluorine, difluorometilo, among others l is Preferred trifluorcarbono Dimethyl, cyclopropyl, among others r1 is h Fluorine R2 is benzyl substituted with 1 to 3 Fluorine substituents, among others.Preferred compounds are: {2 - [1 - (2-fluorobenzyl) - 1H pyrazolo [3,4-b] pyridin-3-yl) - 5-hydroxy-6 - oxo - 6.7 - dihydro - 5h pyrrolo [2,3-d] pyrimidin-5-yl) Tert Butyl acetate, {2 - [1 - (2-fluorobenzyl) - 1H pyrazolo [3,4-b] pyridin-3-yl) - 5-hydroxy-6 - oxo - 6.7 - dihydro - 5h pyrrolo [2,3-d] pyrimidin-5-yl} acetic acid, among others. You. Also refers to a method and a Pharmaceutical composition.These compounds are useful in the treatment of cardiovascular disorders.SE REFIERE A COMPUESTOS PIRIMIDINAS Y TRIAZINAS CONDENSADAS DE FORMULA (I) DONDE A ES N, CR3 R3 ES H, FLUOR, DIFLUOROMETILO, ENTRE OTROS L ES DE PREFERENCIA DIMETIL, CICLOPROPIL, TRIFLUORCARBONO, ENTRE OTROS R1 ES H FLUOR R2 ES BENCILO SUSTITUIDO CON 1 A 3 SUSTITUYENTES FLUOR, ENTRE OTROS. SON COMPUESTOS PREFERIDOS: {2-[1-(2-FLUOROBENCIL)-1H-PIRAZOLO[3,4-b]PIRIDIN-3-IL]-5-HIDROXI-6-OXO-6,7-DIHIDRO-5H-PIRROLO[2,3-d]PIRIMIDIN-5-IL}ACETATO DE TERC-BUTILO, {2-[1-(2-FLUOROBENCIL)-1H-PIRAZOLO[3,4-b]PIRIDIN-3-IL]-5-HIDROXI-6-OXO-6,7-DIHIDRO-5H-PIRROLO[2,3-d]PIRIMIDIN-5-IL}ACETICO, ENTRE OTROS. SE REFIERE TAMBIEN A UN PROCEDIMIENTO Y UNA COMPOSICION FARMACEUTICA. DICHOS COMPUESTOS SON UTILES EN EL TRATAMIENTO DE TRASTORNOS CARDIOVASCULARES.
