DENNIS MARK,WATTS RYAN JEFFERSON,YU YUNHUA JOY,ZHANG YIN
申请号：
NZ70675111
公开号：
NZ706751A
申请日:
2011.11.29
申请国别(地区):
NZ
年份:
2016
代理人:
摘要：
Disclosed are antibodies with low affinity to a blood brain barrier receptor which may be coupled to compounds for transportation of the compounds across the blood brain barrier. Further disclosed are therapeutic uses and methods thereof of said antibodies. Further disclosed are bispecific antibodies which bind transferrin receptor with a low affinity and a second brain antigen.
