SENTER, PETER D.,DORONINA, SVETLANA,TOKI, BRIAN E.
申请号:
CA2494105
公开号:
CA2494105C
申请日:
2003.07.31
申请国别(地区):
CA
年份:
2013
代理人:
摘要:
Drug-Linker-Ligand Conjugates are disclosed in which a Drug is linked to aLigand via a peptide-based Linker unit. In one embodiment, the Ligand is anAntibody. Drug-Linker compounds and Drug compounds are also disclosed. Methodsfor treating cancer, an autoimmune disease or an infectious disease using thecompounds and compositions of the invention are also disclosed.