SENTER PETER D.,Senter Peter D.,DORONINA SVETLANA,Doronina Svetlana,TOKI BRIAN E.,Toki Brian E.
申请号:
SI200332457
公开号:
SI2357006T1
申请日:
2003.07.31
申请国别(地区):
SI
年份:
2016
代理人:
摘要:
Drug-Linker-Ligand Conjugates are disclosed in which a Drug is linked to a Ligand via a peptide-based Linker unit. In one embodiment, the Ligand is an Antibody. Drug-Linker compounds and Drug compounds are also disclosed. Methods for treating cancer, an autoimmune disease or an infectious disease using the compounds and compositions of the invention are also disclosed.