Peter D. Senter,Svetlana O. Doronina,Brian E. Toki
申请号：
US12880028
公开号：
US08906376B2
申请日:
2010.09.10
申请国别(地区):
US
年份:
2014
代理人:
摘要：
Drug-Linker-Ligand Conjugates are disclosed in which a Drug is linked to a Ligand via a peptide-based Linker unit. In one embodiment, the Ligand is an Antibody. Drug-Linker compounds and Drug compounds are also disclosed. Methods for treating cancer, an autoimmune disease or an infectious disease using the compounds and compositions of the invention are also disclosed.
