FLUORESCENT DYE COMPOUND AND LIPOSOME COMPRISING THE SAME

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专利权人:

发明人:

HAYASHI HIDEKI,FUJINAMI MASANORI,TOYOTA TARO,TAMURA YUTAKA,AOKI AKIRA,MURAKI YUTAKA,ONOUE KAZUKI

申请号：

IN10851/CHENP/2012

公开号：

IN299524B

申请日:

2011.05.31

申请国别(地区):

IN

年份:

2018

代理人:

摘要：

Disclosed is a near-infrared fluorescent imaging agent comprising an indocyanine-based fluorescent dye and a liposome. The near-infrared fluorescent imaging agent of the present invention demonstrates high fluorescence intensity and a long anchoring time in sentinel lymph nodes, thereby making it useful for detecting sentinel lymph nodes in sentinel lymph node navigation surgery. Also disclosed is an indocyanine green derivative that is particularly suitable for use in the near-infrared fluorescent imaging agent of the present invention. EP2579027A1

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