Fluorescent probe for lymph node imaging

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专利权人:

エーザイ・アール・アンド・ディー・マネジメント株式会社

发明人:

林 秀樹,藤浪 眞紀,豊田 太郎,田村 裕,青木 陽,村木 裕,尾上 和貴

申请号：

JP2016188336

公开号：

JP6240285B2

申请日:

2016.09.27

申请国别(地区):

JP

年份:

2017

代理人:

摘要：

Disclosed is a near-infrared fluorescent imaging agent comprising an indocyanine-based fluorescent dye and a liposome. The near-infrared fluorescent imaging agent of the present invention demonstrates high fluorescence intensity and a long anchoring time in sentinel lymph nodes, thereby making it useful for detecting sentinel lymph nodes in sentinel lymph node navigation surgery. Also disclosed is an indocyanine green derivative that is particularly suitable for use in the near-infrared fluorescent imaging agent of the present invention.

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中国工程科技知识中心

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http://www.ckcest.cn/home/